TXNIP Antibody

• Background:

  TXNIP (Thioredoxin-interacting protein), also called VDUP1 (Vitamin D3 upregulated protein 1) is a member of the Arrestin family of signal transduction proteins. It is a potent tumor suppressor, blocking tumor growth via blocking cell cycle progression, and reduced expression of TXNIP is found in many tumors. One way TXNIP exerts its tumor suppressive function is by suppressing NF-kB activation, possibly via regulation of the NF-kB subunit p65.

• NCBI Gene ID:

  10628

• Swiss Prot:

  Q9H3M7

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A recombinant protein fragment from the N-terminal region of human TXNIP was used as the immunogen for this antibody.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  Protein A affinity chromatography

• Concentration:

  0.5 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at -20˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG

• Symbol:

  TXNIP

• NCBI Official Name:

  Thioredoxin interacting protein

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Thioredoxin-interacting protein, BMP and activin membrane-bound inhibitor homolog, non-metastatic gene A protein, NMA

• Tested Applications:

  WB

• Physical Properties:

  Liquid