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GUCA1B Antibody

CAT: 0223-60-551Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-551Size:400 µL
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Background
The protein encoded by this gene is a calcium-binding protein that activates photoreceptor guanylate cyclases. This gene may have arisen due to a gene duplication event since there is a highly similar gene clustered with it on chromosome 6. Mutations in this gene can cause a form of retinitis pigmentosa. [provided by RefSeq].
NCBI Gene ID
2979
Swiss Prot
Q9UMX6
Accession Number
Q9UMX6
Host
Rabbit
Reactivity
Human
Immunogen
This GUCA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human GUCA1B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
23 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GUCA1B
NCBI Official Name
Guanylyl cyclase-activating protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Sato, M., et al. Graefes Arch. Clin. Exp. Ophthalmol. 243 (3) :235-242 (2005)
Background Reference 02
Nishiguchi, K.M., et al. Invest. Ophthalmol. Vis. Sci. 45 (11) :3863-3870 (2004)
Background Reference 03
Mungall, A.J., et al. Nature 425 (6960) :805-811 (2003)
Background Reference 04
Wistow, G., et al. Mol. Vis. 8, 196-204 (2002) :
Other Product Names
Guanylyl cyclase-activating protein 2, GCAP 2, Guanylate cyclase activator 1B, GUCA1B, GCAP2
Tested Applications
WB
Protein ID
116242507
Physical Properties
Liquid

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