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GUCY1B3 Antibody

CAT: 0223-26-093Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-26-093Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit and a beta subunit, typically GUCY1B3, catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide (NO) and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]) .Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit and a beta subunit, typically GUCY1B3, catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide (NO) and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]) .
NCBI Gene ID
2983
Swiss Prot
Q02153
Accession Number
NP_000848
Host
Rabbit
Reactivity
Human, Mouse, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GUCY1B3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction, Immunology
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GUCY1B3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
70 kDa
Applications Notes
GUCY1B3 antibody can be used for detection of GUCY1B3 by ELISA at 1:12500. GUCY1B3 antibody can be used for detection of GUCY1B3 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
GUCY1B3
NCBI Official Name
Guanylate cyclase 1, soluble, beta 3
NCBI Organism
Homo sapiens
Background Reference 01
Slavov, D., (2006) Int. J. Impot. Res. 18 (5), 432-437.
Other Product Names
GUCY1B3, GC-S-beta-1, GC-SB3, GUC1B3, GUCB3, GUCSB3, GUCY1B1
Tested Applications
ELISA, WB
Protein ID
4504215
Physical Properties
Liquid

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