GUCA2A Antibody

• Background :

  Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.

• NCBI Gene ID :

  2980

• Swiss Prot :

  Q02747

• Accession Number :

  Q02747

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This GUCA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the Central region of human GUCA2A.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Neuroscience, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  12 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  GUCA2A

• NCBI Official Name :

  Guanylin

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Dell'Orco, D., et al. Cell. Mol. Life Sci. 67 (6) :973-984 (2010)

• Background Reference 02 :

  Chen, Y.B., et al. Zhonghua Wei Chang Wai Ke Za Zhi 12 (5) :515-517 (2009)

• Background Reference 03 :

  Albano, F., et al. Pediatr. Res. 58 (1) :159-163 (2005)

• Background Reference 04 :

  Sindic, A., et al. Kidney Int. 67 (4) :1420-1427 (2005)

• Other Product Names :

  Guanylin, Guanylate cyclase activator 2A, Guanylate cyclase-activating protein 1, Guanylate cyclase-activating protein I, GCAP-I, HMW-guanylin, Guanylin, GUCA2A, GUCA2

• Tested Applications :

  WB

• Protein ID :

  290457645

• Physical Properties :

  Liquid