GUCA2A Antibody

• Background:

  Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.

• NCBI Gene ID:

  2980

• Swiss Prot:

  Q02747

• Accession Number:

  Q02747

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GUCA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the Central region of human GUCA2A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  12 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  GUCA2A

• NCBI Official Name:

  Guanylin

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Dell'Orco, D., et al. Cell. Mol. Life Sci. 67 (6) :973-984 (2010)

• Background Reference 02:

  Chen, Y.B., et al. Zhonghua Wei Chang Wai Ke Za Zhi 12 (5) :515-517 (2009)

• Background Reference 03:

  Albano, F., et al. Pediatr. Res. 58 (1) :159-163 (2005)

• Background Reference 04:

  Sindic, A., et al. Kidney Int. 67 (4) :1420-1427 (2005)

• Other Product Names:

  Guanylin, Guanylate cyclase activator 2A, Guanylate cyclase-activating protein 1, Guanylate cyclase-activating protein I, GCAP-I, HMW-guanylin, Guanylin, GUCA2A, GUCA2

• Tested Applications:

  WB

• Protein ID:

  290457645

• Physical Properties:

  Liquid