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CD1D Antibody

CAT: 0223-58-878Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-878Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail.
NCBI Gene ID
912
Swiss Prot
P15813
Accession Number
P15813
Host
Rabbit
Reactivity
Human
Immunogen
This CD1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-206 amino acids from the Central region of human CD1D.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
38 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CD1D
NCBI Official Name
Antigen-presenting glycoprotein CD1d
NCBI Organism
Homo sapiens
Background Reference 01
Miura, S., et al. J. Virol. 84 (22) :11614-11623 (2010)
Background Reference 02
Moll, M., et al. Blood 116 (11) :1876-1884 (2010)
Background Reference 03
Liu, J., et al. J. Immunol. 184 (9) :4973-4981 (2010)
Background Reference 04
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Other Product Names
Antigen-presenting glycoprotein CD1d, R3G1, CD1d, CD1D
Tested Applications
WB
Protein ID
115964
Physical Properties
Liquid

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