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CLCN2 Antibody

CAT: 0223-58-678Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-678Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The transmembrane protein encoded by this gene is a voltage-gated chloride channel that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
1181
Swiss Prot
P51788
Accession Number
P51788
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This CLCN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-237 amino acids from the N-terminal region of human CLCN2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rabbit, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
99 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CLCN2
NCBI Official Name
Chloride channel protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Scheper, G.C., et al. Genet Test Mol Biomarkers 14 (2) :255-257 (2010)
Background Reference 02
Cornejo, I., et al. J. Cell. Physiol. 221 (3) :650-657 (2009)
Background Reference 03
Thompson, C.H., et al. J. Biol. Chem. 284 (38) :26051-26062 (2009)
Background Reference 04
Kleefuss-Lie, A., et al. Nat. Genet. 41 (9) :954-955 (2009)
Other Product Names
Chloride channel protein 2, ClC-2, CLCN2
Tested Applications
WB
Protein ID
288558807
Physical Properties
Liquid

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