CLCN5 Antibody

• Background:

  This gene encodes a member of the ClC family of chloride ion channels and ion transporters. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

• NCBI Gene ID:

  1184

• Swiss Prot:

  P51795

• Accession Number:

  P51795

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CLCN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-41 amino acids from the N-terminal region of human CLCN5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rabbit, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  83 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CLCN5

• NCBI Official Name:

  H (+) /Cl (-) exchange transporter 5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Smith, A.J., et al. FASEB J. 24 (10) :3696-3705 (2010)

• Background Reference 02:

  Wellhauser, L., et al. Pflugers Arch. 460 (2) :543-557 (2010)

• Background Reference 03:

  Smith, A.J., et al. J. Physiol. (Lond.) 588 (PT 12), 2033-2045 (2010) :

• Background Reference 04:

  Picollo, A., et al. J. Gen. Physiol. 135 (6) :653-659 (2010)

• Other Product Names:

  H (+) /Cl (-) exchange transporter 5, Chloride channel protein 5, ClC-5, Chloride transporter ClC-5, CLCN5, CLCK2

• Tested Applications:

  WB

• Physical Properties:

  Liquid