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CLCN7 Antibody

CAT: 0223-22-531Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-22-531Size:100 µL
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Background
The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.
NCBI Gene ID
1186
Swiss Prot
P51798
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 626-805 of human CLCN7 (NP_001278.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
HL-60
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 89kDa/110kDa
Fragment
IgG
Symbol
CLCN7
Positive Control 2
SKOV3
Positive Control 3
BT-474
Positive Control 4
NCI-H460
Positive Control 5
Mouse liver
Positive Control 6
Rat liver
NCBI Official Name
H (+) /Cl (-) exchange transporter 7
NCBI Organism
Homo sapiens
Other Product Names
H (+) /Cl (-) exchange transporter 7, Chloride channel 7 alpha subunit, Chloride channel protein 7, ClC-7, CLCN7
Tested Applications
WB, IHC
Physical Properties
Liquid

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