CLCN5 Antibody

• Background:

  This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

• NCBI Gene ID:

  1184

• Swiss Prot:

  P51795

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 637-816 of human CLCN5 (NP_001121370.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  SW480

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 100kDa

• Fragment:

  IgG

• Symbol:

  CLCN5

• Positive Control 2:

  U-937

• Positive Control 3:

  HepG2

• Positive Control 4:

  A673

• Positive Control 5:

  NCI-H460

• Positive Control 6:

  Mouse kidney

• NCBI Official Name:

  H (+) /Cl (-) exchange transporter 5

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  H (+) /Cl (-) exchange transporter 5, Chloride channel protein 5, ClC-5, Chloride transporter ClC-5, CLCN5, CLCK2

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid