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RAD1 Antibody

CAT: 0223-58-203Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-203Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq].
NCBI Gene ID
5810
Swiss Prot
O60671
Accession Number
O60671
Host
Rabbit
Reactivity
Human
Immunogen
This RAD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-146 amino acids from the Central region of human RAD1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
32 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RAD1
NCBI Official Name
Cell cycle checkpoint protein RAD1
NCBI Organism
Homo sapiens
Background Reference 01
Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)
Background Reference 02
Takeishi, Y., et al. Genes Cells 15 (7) :761-771 (2010)
Background Reference 03
Bai, H., et al. DNA Repair (Amst.) 9 (5) :478-487 (2010)
Background Reference 04
Park, M.J., et al. DNA Repair (Amst.) 8 (10) :1190-1200 (2009)
Other Product Names
Cell cycle checkpoint protein RAD1, hRAD1, DNA repair exonuclease rad1 homolog, Rad1-like DNA damage checkpoint protein, RAD1, REC1
Tested Applications
WB
Physical Properties
Liquid

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