RAD9 Antibody

• Background:

  Rad9 is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade.

• NCBI Gene ID:

  5883

• Swiss Prot:

  Q99638

• Accession Number:

  Q99638

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RAD9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-279 amino acids from the Central region of human RAD9.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Monkey

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  43 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  RAD9A

• NCBI Official Name:

  Cell cycle checkpoint control protein RAD9A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Maniwa, Y., et al., Cancer 103 (1) :126-132 (2005) .

• Background Reference 02:

  Wang, W., et al., Proc. Natl. Acad. Sci. U.S.A. 101 (48) :16762-16767 (2004) .

• Background Reference 03:

  Lindsey-Boltz, L.A., et al., (er) Nucleic Acids Res. 32 (15) :4524-4530 (2004) .

• Background Reference 04:

  Toueille, M., et al., (er) Nucleic Acids Res. 32 (11) :3316-3324 (2004) .

• Other Product Names:

  Cell cycle checkpoint control protein RAD9A, hRAD9, DNA repair exonuclease rad9 homolog A, RAD9A

• Tested Applications:

  WB

• Protein ID:

  74717382

• Physical Properties:

  Liquid