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Rad9 Antibody

CAT: 0223-55-891Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-891Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene.
NCBI Gene ID
5883
Swiss Prot
Q99638
Accession Number
Q99638
Host
Rabbit
Reactivity
Human
Immunogen
This Rad9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 365-391 amino acids from human Rad9.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
43 kDa
Fragment
Rabbit Ig
Symbol
RAD9A
NCBI Official Name
Cell cycle checkpoint control protein RAD9A
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Takeishi, Y., et al. Genes Cells 15 (7) :761-771 (2010)
Background Reference 03
Greer Card, D.A., et al. J. Biol. Chem. 285 (20) :15653-15661 (2010)
Background Reference 04
Bai, H., et al. DNA Repair (Amst.) 9 (5) :478-487 (2010)
Other Product Names
Cell cycle checkpoint control protein RAD9A, hRAD9, DNA repair exonuclease rad9 homolog A, RAD9A
Tested Applications
WB, IHC-P, IF
Protein ID
74717382
Physical Properties
Liquid

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