Mouse Map4k2 Antibody

• Background:

  Enhances MAP3K1 oligomerization, which may relieve amino-terminal mediated MAP3K1 autoinhibition and lead to activation following autophosphorylation. May play a role in the regulation of vesicle targeting or fusion.

• NCBI Gene ID:

  26412

• Swiss Prot:

  Q61161

• Accession Number:

  Q61161

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This Mouse Map4k2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 432-459 amino acids from the Central region of mouse Map4k2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  91 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  Map4k2

• NCBI Official Name:

  Mitogen-activated protein kinase kinase kinase kinase 2

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Zhong, J., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (11) :4372-4377 (2009)

• Background Reference 02:

  Ren, M., et al. Proc. Natl. Acad. Sci. U.S.A. 93 (10) :5151-5155 (1996)

• Other Product Names:

  Mitogen-activated protein kinase kinase kinase kinase 2, Germinal center kinase, GCK, MAPK/ERK kinase kinase kinase 2, MEK kinase kinase 2, MEKKK 2, Rab8-interacting protein, Map4k2, Rab8ip

• Tested Applications:

  WB

• Physical Properties:

  Liquid