Mouse Map2k1 Antibody

• Background:

  Map2k1 catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.

• NCBI Gene ID:

  26395

• Swiss Prot:

  P31938

• Accession Number:

  P31938

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This Mouse Map2k1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-296 amino acids from the C-terminal region of mouse Map2k1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Hamster, Rabbit, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  43 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  Map2k1

• NCBI Official Name:

  Dual specificity mitogen-activated protein kinase kinase 1

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Chandrakesan, P., et al. J. Biol. Chem. 285 (43) :33485-33498 (2010)

• Background Reference 02:

  Yang, T., et al. J. Clin. Invest. 120 (7) :2474-2485 (2010)

• Background Reference 03:

  Cho, K.W., et al. J. Exp. Zool.Mol. Dev. Evol. 312 (8) :901-911 (2009)

• Background Reference 04:

  Jo, C., et al. Cell. Signal. 21 (12) :1910-1917 (2009)

• Other Product Names:

  Dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1, MAPKK 1, ERK activator kinase 1, MAPK/ERK kinase 1, MEK 1, Map2k1, Mek1, Prkmk1

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid