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Mouse Map2k5 Antibody

CAT: 0223-57-517Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-517Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Map2k5 acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.
NCBI Gene ID
23938
Swiss Prot
Q9WVS7
Accession Number
Q9WVS7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Mouse Map2k5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-412 amino acids from the C-terminal region of mouse Map2k5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
50 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Map2k5
NCBI Official Name
Dual specificity mitogen-activated protein kinase kinase 5
NCBI Organism
Mus musculus
Background Reference 01
Spiering, D., et al. J. Biol. Chem. 284 (37) :24972-24980 (2009)
Background Reference 02
Carter, E.J., et al. J. Cell. Sci. 122 (PT 17), 3104-3112 (2009) :
Background Reference 03
Sohn, S.J., et al. EMBO J. 27 (13) :1896-1906 (2008)
Background Reference 04
Shishido, T., et al. Circ. Res. 102 (11) :1416-1425 (2008)
Other Product Names
Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MAPK/ERK kinase 5, MEK 5, Map2k5, Mek5, Mkk5, Prkmk5
Tested Applications
WB
Physical Properties
Liquid

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