Mouse Map4k4 Antibody

• Background :

  Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway.

• NCBI Gene ID :

  26921

• Swiss Prot :

  P97820

• Accession Number :

  P97820

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This Mouse Map4k4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 506-534 amino acids from the Central region of mouse Map4k4.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  141 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  Map4k4

• NCBI Official Name :

  Mitogen-activated protein kinase kinase kinase kinase 4

• NCBI Organism :

  Mus musculus

• Background Reference 01 :

  Maruyama, T., et al. J. Bone Miner. Res. 25 (5) :1058-1067 (2010)

• Background Reference 02 :

  Guntur, K.V., et al. J. Biol. Chem. 285 (9) :6595-6603 (2010)

• Background Reference 03 :

  Aouadi, M., et al. Nature 458 (7242) :1180-1184 (2009)

• Background Reference 04 :

  Wittwer, T., et al. Biochem. Biophys. Res. Commun. 371 (2) :294-297 (2008)

• Other Product Names :

  Mitogen-activated protein kinase kinase kinase kinase 4, HPK/GCK-like kinase HGK, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, Nck-interacting kinase, Map4k4, Nik

• Tested Applications :

  WB

• Physical Properties :

  Liquid