Mouse Map4k4 Antibody

• Background:

  Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway.

• NCBI Gene ID:

  26921

• Swiss Prot:

  P97820

• Accession Number:

  P97820

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This Mouse Map4k4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 506-534 amino acids from the Central region of mouse Map4k4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  141 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  Map4k4

• NCBI Official Name:

  Mitogen-activated protein kinase kinase kinase kinase 4

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Maruyama, T., et al. J. Bone Miner. Res. 25 (5) :1058-1067 (2010)

• Background Reference 02:

  Guntur, K.V., et al. J. Biol. Chem. 285 (9) :6595-6603 (2010)

• Background Reference 03:

  Aouadi, M., et al. Nature 458 (7242) :1180-1184 (2009)

• Background Reference 04:

  Wittwer, T., et al. Biochem. Biophys. Res. Commun. 371 (2) :294-297 (2008)

• Other Product Names:

  Mitogen-activated protein kinase kinase kinase kinase 4, HPK/GCK-like kinase HGK, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, Nck-interacting kinase, Map4k4, Nik

• Tested Applications:

  WB

• Physical Properties:

  Liquid