Mouse Map3k3 Antibody

• Background:

  Component of a protein kinase signal transduction cascade. Map3k3 mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators.

• NCBI Gene ID:

  26406

• Swiss Prot:

  Q61084

• Accession Number:

  Q61084

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This Mouse Map3k3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the Central region of mouse Map3k3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  71 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  Map3k3

• NCBI Official Name:

  Mitogen-activated protein kinase kinase kinase 3

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Zhang, J., et al. J. Immunol. 185 (6) :3554-3563 (2010)

• Background Reference 02:

  Yu, L., et al. Cancer Res. 70 (4) :1334-1343 (2010)

• Background Reference 03:

  Sun, W., et al. Cell. Signal. 21 (10) :1488-1494 (2009)

• Background Reference 04:

  Retting, K.N., et al. Development 136 (7) :1093-1104 (2009)

• Other Product Names:

  Mitogen-activated protein kinase kinase kinase 3, MAPK/ERK kinase kinase 3, MEK kinase 3, MEKK 3, Map3k3, Mekk3

• Tested Applications:

  WB

• Physical Properties:

  Liquid