Mouse Map3k3 Antibody

• Background :

  Component of a protein kinase signal transduction cascade. Map3k3 mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators.

• NCBI Gene ID :

  26406

• Swiss Prot :

  Q61084

• Accession Number :

  Q61084

• Host :

  Rabbit

• Reactivity :

  Mouse

• Immunogen :

  This Mouse Map3k3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the Central region of mouse Map3k3.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Immunology, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  71 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  Map3k3

• NCBI Official Name :

  Mitogen-activated protein kinase kinase kinase 3

• NCBI Organism :

  Mus musculus

• Background Reference 01 :

  Zhang, J., et al. J. Immunol. 185 (6) :3554-3563 (2010)

• Background Reference 02 :

  Yu, L., et al. Cancer Res. 70 (4) :1334-1343 (2010)

• Background Reference 03 :

  Sun, W., et al. Cell. Signal. 21 (10) :1488-1494 (2009)

• Background Reference 04 :

  Retting, K.N., et al. Development 136 (7) :1093-1104 (2009)

• Other Product Names :

  Mitogen-activated protein kinase kinase kinase 3, MAPK/ERK kinase kinase 3, MEK kinase 3, MEKK 3, Map3k3, Mekk3

• Tested Applications :

  WB

• Physical Properties :

  Liquid