PDE8A Antibody

• Background :

  PDE8A plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase, which has a high affinity for cAMP, may be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.

• NCBI Gene ID :

  5151

• Swiss Prot :

  O60658

• Accession Number :

  O60658

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This PDE8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557-587 amino acids from the Central region of human PDE8A.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  93 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  PDE8A

• NCBI Official Name :

  High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Wu, P., Proc. Natl. Acad. Sci. U.S.A. 101 (51), 17634-17639 (2004)

• Background Reference 02 :

  Gamanuma, M., Cell. Signal. 15 (6), 565-574 (2003)

• Other Product Names :

  High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, PDE8A

• Tested Applications :

  WB, IHC-P

• Physical Properties :

  Liquid