Mouse Acvr2b Antibody

• Background:

  On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.

• NCBI Gene ID:

  11481

• Swiss Prot:

  P27040

• Accession Number:

  P27040

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This Mouse Acvr2b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the Central region of mouse Acvr2b.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  61 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  Acvr2b

• NCBI Official Name:

  Activin receptor type-2B

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Natale, D.R., et al. Dev. Biol. 335 (1) :120-131 (2009)

• Background Reference 02:

  Gamer, L.W., et al. Dev. Dyn. 238 (9) :2374-2381 (2009)

• Background Reference 03:

  Yamamoto, M., et al. J. Cell Biol. 184 (2) :323-334 (2009)

• Background Reference 04:

  Morita, S., et al. PLoS ONE (1), E4212 (2009) :

• Other Product Names:

  Activin receptor type-2B, Activin receptor type IIB, ACTR-IIB, Acvr2b

• Tested Applications:

  WB

• Physical Properties:

  Liquid