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Mouse Acvr2b Antibody

CAT: 0223-57-347Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-347Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
NCBI Gene ID
11481
Swiss Prot
P27040
Accession Number
P27040
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Mouse Acvr2b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the Central region of mouse Acvr2b.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
61 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Acvr2b
NCBI Official Name
Activin receptor type-2B
NCBI Organism
Mus musculus
Background Reference 01
Natale, D.R., et al. Dev. Biol. 335 (1) :120-131 (2009)
Background Reference 02
Gamer, L.W., et al. Dev. Dyn. 238 (9) :2374-2381 (2009)
Background Reference 03
Yamamoto, M., et al. J. Cell Biol. 184 (2) :323-334 (2009)
Background Reference 04
Morita, S., et al. PLoS ONE (1), E4212 (2009) :
Other Product Names
Activin receptor type-2B, Activin receptor type IIB, ACTR-IIB, Acvr2b
Tested Applications
WB
Physical Properties
Liquid

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