ACVR2A Antibody

CAT: 0223-18-428Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-18-428Size:100 µL
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Background
This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.
NCBI Gene ID
92
Swiss Prot
P27037
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-140 of human ACVR2A (NP_001607.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
SW480
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 57kDa
Fragment
IgG
Symbol
ACVR2A
Positive Control 2
Mouse kidney
Positive Control 3
Rat testis
Positive Control 4
Rat ovary
NCBI Official Name
Activin A receptor, type IIA
NCBI Organism
Homo sapiens
Other Product Names
ACVR2A, ACTRIIA, Activin receptor type IIA, ACTRII, Activin A receptor type II, Activin receptor type-2A, ACTR-IIA, Activin A receptor, type II, Activin A receptor, type IIA, ACVR2
Tested Applications
WB, IHC, IF
Physical Properties
Liquid

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MBS859696-01ACVR2A Antibody

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