Mouse Acvr2a Antibody

• Background :

  On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.

• NCBI Gene ID :

  11480

• Swiss Prot :

  P27038

• Accession Number :

  P27038

• Host :

  Rabbit

• Reactivity :

  Mouse

• Immunogen :

  This Mouse Acvr2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-49 amino acids from the N-terminal region of mouse Acvr2a.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  58 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  Acvr2a

• NCBI Official Name :

  Activin receptor type-2A

• NCBI Organism :

  Mus musculus

• Background Reference 01 :

  Perron, J.C., et al. PLoS ONE (12), E8198 (2009) :

• Background Reference 02 :

  Morita, S., et al. PLoS ONE (1), E4212 (2009) :

• Background Reference 03 :

  Kamiya, N., et al. Development 135 (22) :3801-3811 (2008)

• Background Reference 04 :

  Xia, Y., et al. J. Biol. Chem. 282 (25) :18129-18140 (2007)

• Other Product Names :

  Activin receptor type-2A, Activin receptor type IIA, ACTR-IIA, Acvr2a, Acvr2

• Tested Applications :

  WB

• Physical Properties :

  Liquid