Mouse Acvr1c Antibody

CAT: 0223-57-853Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-853Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
NCBI Gene ID
269275
Swiss Prot
Q8K348
Accession Number
Q8K348
Host
Rabbit
Reactivity
Mouse
Immunogen
This Mouse Acvr1c antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-368 amino acids from the C-terminal region of mouse Acvr1c.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Human, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
55 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Acvr1c
NCBI Official Name
Activin receptor type-1C
NCBI Organism
Mus musculus
Background Reference 01
Andersson, O., et al. Proc. Natl. Acad. Sci. U.S.A. 105 (20) :7252-7256 (2008)
Background Reference 02
Bertolino, P., et al. Proc. Natl. Acad. Sci. U.S.A. 105 (20) :7246-7251 (2008)
Background Reference 03
Liguori, G.L., et al. Dev. Biol. 315 (2) :280-289 (2008)
Background Reference 04
Kurrasch, D.M., et al. J. Neurosci. 27 (50) :13624-13634 (2007)
Other Product Names
Activin receptor type-1C, Activin receptor type IC, ACTR-IC, Activin receptor-like kinase 7, ALK-7, Acvr1c {ECO:0000312|EMBL:AAH287801}
Tested Applications
WB
Physical Properties
Liquid

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