EIF2B5 Antibody

CAT: 0223-56-847Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-847Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
NCBI Gene ID
8893
Swiss Prot
Q13144
Accession Number
Q13144
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This EIF2B5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-65 amino acids from the N-terminal region of human EIF2B5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
80 kDa
Fragment
Rabbit Ig
Symbol
EIF2B5
NCBI Official Name
Translation initiation factor eIF-2B subunit epsilon
NCBI Organism
Homo sapiens
Background Reference 01
Van der Lei, H.D., et al. Neurology 75 (17) :1555-1559 (2010)
Background Reference 02
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 03
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Background Reference 04
Pronk, J., et al. Mult. Scler. 14 (8) :1123-1126 (2008)
Other Product Names
Translation initiation factor eIF-2B subunit epsilon, eIF-2B GDP-GTP exchange factor subunit epsilon, EIF2B5, EIF2BE
Tested Applications
WB, IHC-P
Protein ID
160359049
Physical Properties
Liquid

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