EIF2B5 Antibody

• Background :

  This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

• NCBI Gene ID :

  8893

• Swiss Prot :

  Q13144

• Accession Number :

  Q13144

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This EIF2B5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-65 amino acids from the N-terminal region of human EIF2B5.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  80 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  EIF2B5

• NCBI Official Name :

  Translation initiation factor eIF-2B subunit epsilon

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Van der Lei, H.D., et al. Neurology 75 (17) :1555-1559 (2010)

• Background Reference 02 :

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 03 :

  Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

• Background Reference 04 :

  Pronk, J., et al. Mult. Scler. 14 (8) :1123-1126 (2008)

• Other Product Names :

  Translation initiation factor eIF-2B subunit epsilon, eIF-2B GDP-GTP exchange factor subunit epsilon, EIF2B5, EIF2BE

• Tested Applications :

  WB, IHC-P

• Protein ID :

  160359049

• Physical Properties :

  Liquid