EIF2B4 Antibody

• Background :

  Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

• NCBI Gene ID :

  8890

• Swiss Prot :

  Q9UI10

• Accession Number :

  Q9UI10

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This EIF2B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-175 amino acids from the Central region of human EIF2B4.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  58 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  EIF2B4

• NCBI Official Name :

  Translation initiation factor eIF-2B subunit delta

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Naukkarinen, J., et al. PLoS Genet. (6), E1000976 (2010) :

• Background Reference 02 :

  Wu, Y., et al. J. Hum. Genet. 54 (2) :74-77 (2009)

• Background Reference 03 :

  Horzinski, L., et al. PLoS ONE (12), E8318 (2009) :

• Background Reference 04 :

  Pronk, J., et al. Mult. Scler. 14 (8) :1123-1126 (2008)

• Other Product Names :

  Translation initiation factor eIF-2B subunit delta, eIF-2B GDP-GTP exchange factor subunit delta, EIF2B4, EIF2BD

• Tested Applications :

  WB, IHC-P

• Protein ID :

  28381357

• Physical Properties :

  Liquid