EIF2B3 Antibody

• Background:

  The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  8891

• Swiss Prot:

  Q9NR50

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human EIF2B3 (NP_065098.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 50kDa

• Fragment:

  IgG

• Symbol:

  EIF2B3

• Positive Control 2:

  K-562

• Positive Control 3:

  HT-29

• Positive Control 4:

  Mouse heart

• Positive Control 5:

  Mouse lung

• Positive Control 6:

  Mouse brain

• NCBI Official Name:

  Translation initiation factor eIF-2B subunit gamma

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Translation initiation factor eIF-2B subunit gamma, eIF-2B GDP-GTP exchange factor subunit gamma, EIF2B3

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid