EIF2B3 Antibody

• Background :

  The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID :

  8891

• Swiss Prot :

  Q9NR50

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human EIF2B3 (NP_065098.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Affinity purification

• Positive Control :

  HepG2

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 50kDa

• Fragment :

  IgG

• Symbol :

  EIF2B3

• Positive Control 2 :

  K-562

• Positive Control 3 :

  HT-29

• Positive Control 4 :

  Mouse heart

• Positive Control 5 :

  Mouse lung

• Positive Control 6 :

  Mouse brain

• NCBI Official Name :

  Translation initiation factor eIF-2B subunit gamma

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Translation initiation factor eIF-2B subunit gamma, eIF-2B GDP-GTP exchange factor subunit gamma, EIF2B3

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid