EIF2S2 Antibody

• Background:

  Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation.

• NCBI Gene ID:

  8894

• Swiss Prot:

  P20042

• Accession Number:

  P20042

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This EIF2S2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-299 amino acids from the C-terminal region of human EIF2S2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rabbit

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  38 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  EIF2S2

• NCBI Official Name:

  Eukaryotic translation initiation factor 2 subunit 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rajesh, K., et al. Biochem. Biophys. Res. Commun. 374 (2) :336-340 (2008)

• Background Reference 02:

  Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

• Background Reference 03:

  Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

• Background Reference 04:

  Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

• Other Product Names:

  Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit beta, eIF-2-beta, EIF2S2, EIF2B

• Tested Applications:

  WB

• Protein ID:

  12644154

• Physical Properties:

  Liquid