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TLE4 Antibody

CAT: 0223-56-757Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-757Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TLE4 is a transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity) .
NCBI Gene ID
7091
Swiss Prot
Q04727
Accession Number
Q04727
Host
Rabbit
Reactivity
Human
Immunogen
This TLE4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 167-196 amino acids from the N-terminal region of human TLE4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
84 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TLE4
NCBI Official Name
Transducin-like enhancer protein 4
NCBI Organism
Homo sapiens
Background Reference 01
Liu, Y., et al. PLoS Genet. (11), E1000707 (2009) :
Background Reference 02
Hancock, D.B., et al. PLoS Genet. (8), E1000623 (2009) :
Background Reference 03
Stolk, L., et al. Nat. Genet. (2009) In press :
Background Reference 04
Dayyani, F., et al. Blood 111 (8) :4338-4347 (2008)
Other Product Names
Transducin-like enhancer protein 4, Grg-4, Groucho-related protein 4, TLE4, GRG4, KIAA1261
Tested Applications
WB
Protein ID
158518541
Physical Properties
Liquid

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