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TLE2 Antibody

CAT: 0223-56-312Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-312Size:400 µL
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Background
TLE2 is a transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity) .
NCBI Gene ID
7089
Swiss Prot
Q04725
Accession Number
Q04725
Host
Rabbit
Reactivity
Mouse
Immunogen
This TLE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 637-665 amino acids from the C-terminal region of human TLE2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
80 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TLE2
NCBI Official Name
Transducin-like enhancer protein 2
NCBI Organism
Homo sapiens
Background Reference 01
He, Z., et al. J. Virol. 84 (4) :2047-2062 (2010)
Background Reference 02
Arce, L., et al. BMC Cancer 9, 159 (2009) :
Background Reference 03
Higa, L.A., et al. Nat. Cell Biol. 8 (11) :1277-1283 (2006)
Background Reference 04
Javed, A., et al. J. Cell. Sci. 113 (PT 12), 2221-2231 (2000) :
Other Product Names
Transducin-like enhancer protein 2, Enhancer of split groucho-like protein 2, ESG2, TLE2
Tested Applications
WB
Protein ID
20532416
Physical Properties
Liquid

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