TLE2 Antibody

• Background:

  TLE2 is a transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity) .

• NCBI Gene ID:

  7089

• Swiss Prot:

  Q04725

• Accession Number:

  Q04725

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This TLE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 637-665 amino acids from the C-terminal region of human TLE2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  80 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  TLE2

• NCBI Official Name:

  Transducin-like enhancer protein 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  He, Z., et al. J. Virol. 84 (4) :2047-2062 (2010)

• Background Reference 02:

  Arce, L., et al. BMC Cancer 9, 159 (2009) :

• Background Reference 03:

  Higa, L.A., et al. Nat. Cell Biol. 8 (11) :1277-1283 (2006)

• Background Reference 04:

  Javed, A., et al. J. Cell. Sci. 113 (PT 12), 2221-2231 (2000) :

• Other Product Names:

  Transducin-like enhancer protein 2, Enhancer of split groucho-like protein 2, ESG2, TLE2

• Tested Applications:

  WB

• Protein ID:

  20532416

• Physical Properties:

  Liquid