TLE3 Antibody

• Background:

  The TLE genes are differentially expressed and encode nuclear proteins, consistent with the presence of sequence motifs associated with nuclear functions. These genes are the human homologues of Drosophila groucho, a member of the Notch signaling pathway which controls a number of different cell-fate choices in invertebrates and vertebrates.

• NCBI Gene ID:

  7090

• Swiss Prot:

  Q04726

• Accession Number:

  NP_005069

• Host:

  Rabbit

• Reactivity:

  Human, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TLE3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TLE3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  83 kDa

• Applications Notes:

  TLE3 antibody can be used for detection of TLE3 by ELISA at 1:62500. TLE3 antibody can be used for detection of TLE3 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  TLE3

• NCBI Official Name:

  Transducin-like enhancer of split 3 (E (sp1) homolog, Drosophila)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Liu, Y., et al., (1996) Genomics 31 (1), 58-64.

• Other Product Names:

  TLE3, ESG, ESG3, GRG3, HsT18976

• Tested Applications:

  ELISA, WB

• Protein ID:

  157384982

• Physical Properties:

  Liquid