ONECUT1 Antibody

• Background:

  ONECUT1 is a transcriptional activator. It binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.

• NCBI Gene ID:

  3175

• Swiss Prot:

  Q9UBC0

• Accession Number:

  Q9UBC0

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ONECUT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 356-385 amino acids from the C-terminal region of human ONECUT1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  51 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ONECUT1

• NCBI Official Name:

  Hepatocyte nuclear factor 6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lee, Y.S., et al. Biochem. J. 413 (3) :559-569 (2008)

• Background Reference 02:

  Jiang, X., et al. Oncol. Rep. 19 (1) :157-163 (2008)

• Background Reference 03:

  Lehner, F., et al. FASEB J. 21 (7) :1445-1462 (2007)

• Background Reference 04:

  Rausa, F.M. III, et al. J. Biol. Chem. 279 (41) :43070-43076 (2004)

• Other Product Names:

  Hepatocyte nuclear factor 6, HNF-6, One cut domain family member 1, One cut homeobox 1, ONECUT1, HNF6, HNF6A

• Tested Applications:

  WB

• Protein ID:

  13627184

• Physical Properties:

  Liquid