ONECUT1 Antibody

• Background :

  ONECUT1 is a transcriptional activator. It binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.

• NCBI Gene ID :

  3175

• Swiss Prot :

  Q9UBC0

• Accession Number :

  Q9UBC0

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This ONECUT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 356-385 amino acids from the C-terminal region of human ONECUT1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Obesity, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  51 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  ONECUT1

• NCBI Official Name :

  Hepatocyte nuclear factor 6

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Lee, Y.S., et al. Biochem. J. 413 (3) :559-569 (2008)

• Background Reference 02 :

  Jiang, X., et al. Oncol. Rep. 19 (1) :157-163 (2008)

• Background Reference 03 :

  Lehner, F., et al. FASEB J. 21 (7) :1445-1462 (2007)

• Background Reference 04 :

  Rausa, F.M. III, et al. J. Biol. Chem. 279 (41) :43070-43076 (2004)

• Other Product Names :

  Hepatocyte nuclear factor 6, HNF-6, One cut domain family member 1, One cut homeobox 1, ONECUT1, HNF6, HNF6A

• Tested Applications :

  WB

• Protein ID :

  13627184

• Physical Properties :

  Liquid