ONECUT3 Antibody

• Background:

  ONECUT3 is transcriptional activator. It binds the consensus DNA sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR (By similarity) .

• NCBI Gene ID:

  390874

• Swiss Prot:

  O60422

• Accession Number:

  O60422

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ONECUT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 393-419 amino acids from the C-terminal region of human ONECUT3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  50 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ONECUT3

• NCBI Official Name:

  One cut domain family member 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Grimwood, J., et al. Nature 428 (6982) :529-535 (2004)

• Background Reference 02:

  Vanhorenbeeck, V., et al. Biochem. Biophys. Res. Commun. 292 (4) :848-854 (2002)

• Background Reference 03:

  Venter, J.C., et al. Science 291 (5507) :1304-1351 (2001)

• Background Reference 04:

  Jacquemin, P., et al. J. Biol. Chem. 274 (5) :2665-2671 (1999)

• Other Product Names:

  One cut domain family member 3, One cut homeobox 3, Transcription factor ONECUT-3, OC-3, ONECUT3

• Tested Applications:

  WB

• Physical Properties:

  Liquid