ONECUT2 Antibody

• Background :

  This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation.

• NCBI Gene ID :

  9480

• Swiss Prot :

  O95948

• Accession Number :

  O95948

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This ONECUT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the N-terminal region of human ONECUT2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  54 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  ONECUT2

• NCBI Official Name :

  One cut domain family member 2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Furuno, K., et al. Genes Immun. 9 (4) :302-308 (2008)

• Background Reference 02 :

  Pike, B.L., et al. Leukemia 22 (5) :1035-1043 (2008)

• Background Reference 03 :

  Rauch, T., et al. Cancer Res. 66 (16) :7939-7947 (2006)

• Background Reference 04 :

  Jacquemin, P., et al. Biochem. Biophys. Res. Commun. 285 (5) :1200-1205 (2001)

• Other Product Names :

  One cut domain family member 2, Hepatocyte nuclear factor 6-beta, HNF-6-beta, One cut homeobox 2, Transcription factor ONECUT-2, OC-2, ONECUT2, HNF6B

• Tested Applications :

  WB

• Physical Properties :

  Liquid