GITR Antibody

• Background :

  GITR is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediates NF-kappaB activation via the TRAF2/NIK pathway.

• NCBI Gene ID :

  8784

• Swiss Prot :

  Q9Y5U5

• Accession Number :

  4759246

• Host :

  Rat

• Reactivity :

  Human

• Immunogen :

  Recombinant human GITR.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Immunology

• Concentration :

  1 mg/ml

• Buffer :

  Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Stable for at least 6 months after receipt when stored at -20˚ C.

• Specificity :

  Recognizes human GITR. Does not cross-react with mouse GITR.

• Applications Notes :

  ELISA: (direct and indirect: 1:5,000-1:10,000) . Flow Cytometry: (1:1,000) . Optimal conditions must be determined individually for each application.

• Symbol :

  TNFRSF18

• NCBI Official Name :

  Tumor necrosis factor receptor superfamily, member 18

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Tumor Necrosis Factor Receptor Superfamily Member 18; Activation-inducible TNFR Family Receptor; Glucocorticoid-induced TNFR-related Protein; CD357; TNFRSF18; AITR

• Tested Applications :

  ELISA, Flow

• Protein ID :

  NP_004186

• Physical Properties :

  Liquid