GITR Antibody

• Background:

  GITR is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediates NF-kappaB activation via the TRAF2/NIK pathway.

• NCBI Gene ID:

  8784

• Swiss Prot:

  Q9Y5U5

• Accession Number:

  4759246

• Host:

  Rat

• Reactivity:

  Human

• Immunogen:

  Recombinant human GITR.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology

• Concentration:

  1 mg/ml

• Buffer:

  Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Stable for at least 6 months after receipt when stored at -20˚ C.

• Specificity:

  Recognizes human GITR. Does not cross-react with mouse GITR.

• Applications Notes:

  ELISA: (direct and indirect: 1:5,000-1:10,000) . Flow Cytometry: (1:1,000) . Optimal conditions must be determined individually for each application.

• Symbol:

  TNFRSF18

• NCBI Official Name:

  Tumor necrosis factor receptor superfamily, member 18

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Tumor Necrosis Factor Receptor Superfamily Member 18; Activation-inducible TNFR Family Receptor; Glucocorticoid-induced TNFR-related Protein; CD357; TNFRSF18; AITR

• Tested Applications:

  ELISA, Flow

• Protein ID:

  NP_004186

• Physical Properties:

  Liquid