GITR Recombinant Protein

• Background:

  Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

• Swiss Prot:

  Q8C4K3

• Accession Number:

  Q8C4K3

• Tag:

  His Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Immunology

• Buffer:

  PBS, pH7.4

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  15.2 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130084C11 product:tumor necrosis factor receptor superfamily, member 18, full insert sequence

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Gurney A.L., et al., 1999, Curr. Biol. 9:215-218.

• Background Reference 02:

  Park MS., et al., 2007, Yonsei Med J 48 (5) : 839-46.

• Other Product Names:

  AITR, GITR, TNFRSF18, CD357

• Tested Applications:

  WB

• Species:

  Mouse

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3