GITR Recombinant Protein

• Background:

  Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

• Swiss Prot:

  Q5M835

• Accession Number:

  Q5M835

• Tag:

  Fc Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Immunology

• Buffer:

  Tris with Glycine, Arginine and NaCl, pH7.5

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  37.2 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  Similar to tumor necrosis factor receptor superfamily, member 18

• NCBI Organism:

  Rattus norvegicus

• Background Reference 01:

  Gurney A.L., et al., 1999, Curr. Biol. 9:215-218.

• Background Reference 02:

  Park MS., et al., 2007, Yonsei Med J 48 (5) : 839-46.

• Other Product Names:

  AITR, GITR, TNFRSF18, CD357

• Tested Applications:

  WB

• Species:

  Rat

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3