GITR Recombinant Protein

• Background :

  Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

• Swiss Prot :

  F7DDV8

• Accession Number :

  F7DDV8

• Tag :

  Fc Tag

• Type :

  Recombinant Proteins

• Source :

  HEK293 cells

• Field of Research :

  Immunology

• Buffer :

  Tris with Glycine, Arginine and NaCl, pH7.5

• Shipping Conditions :

  Room Temp

• Storage Conditions :

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight :

  41.3 kDa

• Applications Notes :

  This recombinant protein can be used for WB. For research use only.

• NCBI Organism :

  Macaca mulatta

• Background Reference 01 :

  Gurney A.L., et al., 1999, Curr. Biol. 9:215-218.

• Background Reference 02 :

  Park MS., et al., 2007, Yonsei Med J 48 (5) : 839-46.

• Other Product Names :

  AITR, GITR, TNFRSF18, CD357

• Tested Applications :

  WB

• Species :

  Rhesus monkey

• Physical Properties :

  Lyophilized

• CAS Number :

  9000-83-3