PRSS1 Antibody

• Background :

  This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7.

• NCBI Gene ID :

  5644

• Swiss Prot :

  P07477

• Accession Number :

  P07477

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This PRSS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-107 amino acids from the Central region of human PRSS1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Obesity, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  27 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  PRSS1

• NCBI Official Name :

  Trypsin-1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Joergensen, M.T., et al. Am. J. Gastroenterol. 105 (8) :1876-1883 (2010)

• Background Reference 02 :

  Gasiorowska, A., et al. Dig. Dis. Sci. (2010) In press :

• Background Reference 03 :

  Szmola, R., et al. J. Med. Genet. 47 (5) :348-350 (2010)

• Background Reference 04 :

  Nakanuma, S., et al. Int. J. Oncol. 36 (4) :793-800 (2010)

• Other Product Names :

  Trypsin-1, Beta-trypsin, Cationic trypsinogen, Serine protease 1, Trypsin I, Alpha-trypsin chain 1, Alpha-trypsin chain 2, PRSS1, TRP1, TRY1, TRYP1

• Tested Applications :

  WB

• Protein ID :

  136408

• Physical Properties :

  Liquid