PRSS3 Antibody

• Background :

  PRSS3 encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. PRSS3 is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene.

• Swiss Prot :

  P35030-1

• Accession Number :

  P35030

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This PRSS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human PRSS3.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Cell Cycle, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment :

  Rabbit Ig

• NCBI Official Name :

  Trypsin-3

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Jiang, G., et al. Gut 59 (11) :1535-1544 (2010)

• Background Reference 02 :

  Nakanishi, J., et al. J. Invest. Dermatol. 130 (4) :944-952 (2010)

• Background Reference 03 :

  Salameh, M.A., et al. J. Biol. Chem. 285 (3) :1939-1949 (2010)

• Background Reference 04 :

  Rosendahl, J., et al. Pancreatology 10 (2-3), 243-249 (2010) :

• Other Product Names :

  Trypsin-3, Brain trypsinogen, Mesotrypsinogen, Serine protease 3, Serine protease 4, Trypsin III, Trypsin IV, PRSS3, PRSS4, TRY3, TRY4

• Tested Applications :

  WB, IHC-P, Flow

• Protein ID :

  209572698

• Physical Properties :

  Liquid