PRSS16 Antibody

• Background :

  This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined.

• NCBI Gene ID :

  10279

• Swiss Prot :

  Q9NQE7

• Accession Number :

  Q9NQE7

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This PRSS16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human PRSS16.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  55 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  PRSS16

• NCBI Official Name :

  Thymus-specific serine protease

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Shi, J., et al. Nature 460 (7256) :753-757 (2009)

• Background Reference 02 :

  Stefansson, H., et al. Nature 460 (7256) :744-747 (2009)

• Background Reference 03 :

  Viken, M.K., et al. Genes Immun. 10 (4) :323-333 (2009)

• Background Reference 04 :

  Lie, B.A., et al. Hum. Immunol. 68 (7) :592-598 (2007)

• Other Product Names :

  Thymus-specific serine protease, 34--, Serine protease 16, PRSS16, TSSP

• Tested Applications :

  WB

• Protein ID :

  13633990

• Physical Properties :

  Liquid