PRSS8 Antibody

• Background:

  This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine.

• NCBI Gene ID:

  5652

• Swiss Prot:

  Q16651

• Accession Number:

  Q16651

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PRSS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-219 amino acids from the Central region of human PRSS8.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  36 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PRSS8

• NCBI Official Name:

  Prostasin

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Chen, Y.W., et al. J. Biol. Chem. 285 (41) :31755-31762 (2010)

• Background Reference 02:

  Chen, M., et al. Mol. Cell. Biochem. 337 (1-2), 259-266 (2010) :

• Background Reference 03:

  Fu, Y.Y., et al. Hum. Reprod. 25 (3) :623-632 (2010)

• Background Reference 04:

  Ko, T., et al. J. Biomed. Biotechnol. 2010, 793843 (2010) :

• Other Product Names:

  Prostasin, 3421-, Channel-activating protease 1, CAP1, Serine protease 8, Prostasin light chain, Prostasin heavy chain, PRSS8

• Tested Applications:

  WB

• Protein ID:

  2833277

• Physical Properties:

  Liquid