PRSS3 Antibody

CAT: 0223-56-124Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-124Size:400 µL
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Background
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene.
NCBI Gene ID
5646
Swiss Prot
P35030
Accession Number
P35030
Host
Rabbit
Reactivity
Human
Immunogen
This PRSS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-163 amino acids from the Central region of human PRSS3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Symbol
PRSS3
NCBI Official Name
Trypsin-3
NCBI Organism
Homo sapiens
Background Reference 01
Jiang, G., et al. Gut 59 (11) :1535-1544 (2010)
Background Reference 02
Nakanishi, J., et al. J. Invest. Dermatol. 130 (4) :944-952 (2010)
Background Reference 03
Salameh, M.A., et al. J. Biol. Chem. 285 (3) :1939-1949 (2010)
Background Reference 04
Rosendahl, J., et al. Pancreatology 10 (2-3), 243-249 (2010) :
Other Product Names
Trypsin-3, Brain trypsinogen, Mesotrypsinogen, Serine protease 3, Serine protease 4, Trypsin III, Trypsin IV, PRSS3, PRSS4, TRY3, TRY4
Tested Applications
WB, IHC-P, Flow
Protein ID
209572698
Physical Properties
Liquid

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