HDAC7 Antibody

• Background:

  Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  51564

• Swiss Prot:

  Q8WUI4

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 400-500 of human HDAC7 (NP_056216.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Immunology, Signal Transduction, Stem Cell

• Purification:

  Affinity purification

• Positive Control:

  NIH/3T3

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 120kDa

• Fragment:

  IgG

• Symbol:

  HDAC7

• Positive Control 2:

  A-549

• Positive Control 3:

  MCF7

• Positive Control 4:

  Jurkat

• Positive Control 5:

  Mouse lung

• Positive Control 6:

  Mouse heart

• NCBI Official Name:

  Histone deacetylase 7

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Histone deacetylase 7, HD7, Histone deacetylase 7A, HD7a, HDAC7, HDAC7A

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid