HDAC8 Antibody

CAT: 0223-28-136Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-28-136Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
55869
Swiss Prot
Q9BY41
Accession Number
NP_060956
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HDAC8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HDAC8 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
42 kDa
Applications Notes
HDAC8 antibody can be used for detection of HDAC8 by ELISA at 1:1562500. HDAC8 antibody can be used for detection of HDAC8 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
HDAC8
NCBI Official Name
Histone deacetylase 8
NCBI Organism
Homo sapiens
Background Reference 01
Balasubramanian, S., (2008) Leukemia 22 (5), 1026-1034.
Other Product Names
HDAC8, HDACL1, RPD3, HD8, WTS, CDA07, CDLS5, MRXS6
Tested Applications
ELISA, WB
Protein ID
8923769
Physical Properties
Liquid

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