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HDAC2 Antibody

CAT: 0223-27-648Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-27-648Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.
NCBI Gene ID
3066
Swiss Prot
Q92769
Accession Number
NP_001518
Host
Rabbit
Reactivity
Human, Mouse, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HDAC2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HDAC2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
55 kDa
Applications Notes
HDAC2 antibody can be used for detection of HDAC2 by ELISA at 1:12500. HDAC2 antibody can be used for detection of HDAC2 by western blot at 0.2-2.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
HDAC2
NCBI Official Name
Histone deacetylase 2
NCBI Organism
Homo sapiens
Background Reference 01
Choi, Y.B., et al., (2004) J.Biol.Chem.279 (49), 50930-50941.
Other Product Names
HDAC2, HD2, RPD3, YAF1
Tested Applications
ELISA, WB, IHC
Protein ID
293336691
Physical Properties
Liquid

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