GRB2 Antibody

CAT: 0223-19-796Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-19-796Size:100 µL
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Background
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
2885
Swiss Prot
P62993
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-217 of human GRB2 (NP_002077.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
SW620
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 33kDa
Fragment
IgG
Symbol
GRB2
Positive Control 2
Raji
Positive Control 3
BT-474
Positive Control 4
HepG2
Positive Control 5
Mouse heart
NCBI Official Name
Growth factor receptor-bound protein 2
NCBI Organism
Homo sapiens
Other Product Names
GRB2, growth factor receptor-bound protein 2, ASH, ASH protein, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, HT027, abundant SRC homology, epidermal growth factor receptor-binding protein GRB2, growth factor receptor-bound protein 3
Tested Applications
WB, IHC, IF
Physical Properties
Liquid

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