GRB7 Antibody

CAT: 0223-63-960Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-63-960Size:400 µL
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Background
GRB7 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK) .
NCBI Gene ID
2886
Swiss Prot
Q14451
Accession Number
Q14451
Host
Rabbit
Reactivity
Human
Immunogen
This GRB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-318 amino acids from the Central region of human GRB7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
60 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GRB7
NCBI Official Name
Growth factor receptor-bound protein 7
NCBI Organism
Homo sapiens
Background Reference 01
Depetris, R.S., et al. Nat. Struct. Mol. Biol. 16 (8) :833-839 (2009)
Background Reference 02
Chu, P.Y., et al. J. Biol. Chem. 284 (30) :20215-20226 (2009)
Background Reference 03
Mavaddat, N., et al. Cancer Epidemiol. Biomarkers Prev. 18 (1) :255-259 (2009)
Background Reference 04
Bai, T., et al. Carcinogenesis 29 (3) :473-479 (2008)
Other Product Names
Growth factor receptor-bound protein 7, B47, Epidermal growth factor receptor GRB-7, GRB7 adapter protein, GRB7
Tested Applications
WB
Protein ID
116242503
Physical Properties
Liquid

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