GRB2 antibody

• Background:

  The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Synonyms:

  Growth factor receptor-bound protein 2|Adapter protein GRB2|Protein Ash|SH2/SH3 adapter GRB2|GRB2|ASH

• Gene ID:

  2885

• UniProt:

  P62993

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Growth factor receptor-bound protein 2

• Target:

  GRB2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IF, IHC

• Field of Research:

  Immunology, Cardiovascular, Signal Transduction

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  33 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IF, IHC