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TrkB Antibody

CAT: 0223-14-225Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-14-225Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
4915
Swiss Prot
Q16620
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 41-433 of human TrkB (NP_001007098.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Growth Factors, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
K-562
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 110kDa
Fragment
IgG
Symbol
NTRK2
Positive Control 2
Rat brain
NCBI Official Name
Neurotrophic tyrosine kinase, receptor, type 2
NCBI Organism
Homo sapiens
Other Product Names
NTRK2, neurotrophic tyrosine kinase, receptor, type 2, GP145-TrkB, TRKB , BDNF/NT-3 growth factors receptor, tyrosine kinase receptor B, BDNF receptor
Tested Applications
WB, IHC
Physical Properties
Liquid

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