Products for Research Use Only
RegisterLogin

TRKC Antibody

CAT: 0223-63-144Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-63-144Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
TRKC, a member of the insuline receptor subfamily of Tyr protein kinases, is a receptor for neurotrophin-3 (NT-3) . Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.
NCBI Gene ID
4916
Swiss Prot
Q16288
Accession Number
Q16288
Host
Rabbit
Reactivity
Human
Immunogen
This TRKC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-61 amino acids from the N-terminal region of human TRKC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey, Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
94 kDa
Fragment
Rabbit Ig
Symbol
NTRK3
NCBI Official Name
NT-3 growth factor receptor
NCBI Organism
Homo sapiens
Background Reference 01
McGregor, L.M., et al., Genomics 22 (2) :267-272 (1994) .
Background Reference 02
Shelton, D.L., et al., J. Neurosci. 15 (1 Pt 2), 477-491 (1995) .
Other Product Names
NT-3 growth factor receptor, GP145-TrkC, Trk-C, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase, NTRK3, TRKC
Tested Applications
WB, IHC-P
Protein ID
134035335
Physical Properties
Liquid

Related Products

CatalogName
63-141TRKA Antibody
63-143TrkA Antibody
18-499TrkB Antibody
14-225TrkB Antibody
63-142TrkA-pY791 Antibody
79-501TrkA (phospho Ser791) Antibody
79-619TrkB (Ab 705) Antibody
79-502TrkB (phospho Tyr705) Antibody
24-384TrkA Antibody [MNAC13], Mouse IgG1
24-385TrkA Antibody [MNAC13], Rabbit IgG

Alternative Products

CatalogName
abx239003GP145-TrkC (TrkC) Antibody
20R-TG005TrkC antibody
GWB-D05A09Anti- TrkC Antibody
MBS176236-01Anti-TrkC antibody
MO15000TrkC

Popular Products