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TrkB (Ab 705) Antibody

CAT: 0223-79-619Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-619Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF) . Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC γ1.
NCBI Gene ID
4915
Swiss Prot
Q16620
Accession Number
NP_001007098.1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
TrkB (Ab-705) antibody was raised against a peptide sequence around aa.703~707 (T-D-Y -Y-R) derived from TrkB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
145 kDa
Specificity
This antibody detects endogenous levels of total TrkB protein.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
NTRK2
NCBI Official Name
Neurotrophic tyrosine kinase, receptor, type 2
NCBI Organism
This antibody was raised against a peptide sequence around aa.703~707 (T-D-Y -Y-R) derived from TrkB
Background Reference 01
Woronowicz A, et al. Glycobiology. 2007 Jan;17 (1) : 10-24. Mojsilovic-Petrovic J, et al. J Neurosci. 2006 Sep 6;26 (36) : 9250-63. Lewis MA, et al. Mol Pharmacol. 2006 Apr;69 (4) : 1396-404. Cai D, et al. Physiol Genomics. 2006 Feb 14;24 (3) : 191-7.
Other Product Names
TRKB, trk-B, GP145-TrkB, BDNF/NT-3 growth factors receptor precursor, GP145-TrkB/GP95-TrkB, NTRK2, Trk-B
Tested Applications
WB
Protein ID
55956790
Physical Properties
Liquid

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